Eivind Lysheim was inspired to study medical technology after a placement at Oslo University Hospital, arranged by Oslo Cancer Cluster in collaboration with Ullern Upper Secondary School.

Studying medtech with cancer patients at heart

Eivind Lysheim

Former Ullern student Eivind Lysheim has been inspired to make a difference for cancer patients

Eivind Lysheim had decided to study economics at university, until a work placement at the Norwegian Radium Hospital caught his interest in 2016, during his last year at Ullern Upper Secondary School.

The placement was arranged by Oslo Cancer Cluster and took place in the Department of Medical Physics. For an entire week Eivind was mentored by Professor Taran Paulsen Hellebust and her co-workers on medical imaging and how radiotherapy is used to treat cancer patients. The Ullern student learnt how to use the machines and how to create a theoretical treatment plan for a former patient.

“I have always been interested in the natural sciences. I felt that the combination of technology and medicine was extremely interesting. It is fascinating how you can use something that is perceived as deadly – such as gamma radiation, x-rays or high energy particles – and cure someone. When I saw the high-tech machines at the hospital, I got a little bit carried away,” Eivind said with a smile.

Eivind immediately changed his application from economics to the mathematics and physics programme with specialisation in biophysics and medical technology at NTNU in Trondheim.

Four years later, Eivind has one year left of his master’s degree and is still intent on working on technology that can improve the lives of cancer patients.

“Cancer can happen to anyone and almost everyone in Norway knows someone who has been affected by it. It is important that we develop the very best treatments for the people who get ill,” Eivind said.

Eivind got in touch with Bente Prestegård, project manager at Oslo Cancer Cluster, who helped him find a summer internship with our member Kongsberg Beam Technology. The company recently acquired funding to develop control systems for proton therapy machines.

“Among medtech students in Norway, proton therapy is probably the most popular area to work in. Everyone dreams about getting a job in this field. This internship has really been like hitting the jackpot for me,” Eivind said.

Kongsberg Beam Technology is developing a system called MAMA-K, which is short for Multi‑Array Multi-Axis Cancer Combat Machine. The machine treats the tumour with a number of simultaneous proton beams and is especially adapted for more mobile tumours, and it can be added to both existing and new proton machines.

Eivind has spent the summer doing research in the offices belonging to Semcon, who is one of Kongsberg Beam Technology’s partners.

Norway is in the process of building its first two proton centres, at Oslo University Hospital and at Haukeland University Hospital. Many medtech students are eager to work at these centres to develop cancer treatments. Moreover, the technology used in proton machines is an intriguing area of research constantly in development, which makes it highly attractive for new students.

“If I can work with proton therapy, I can look forward to a very exciting and varied career, because the field is always changing and you have to continually learn new things,” Eivind said.

Ketil Widerberg, general manager of Oslo Cancer Cluster, leading a debate on health data during EHiN 2019. Photo: Ard Jongsma / Still Words Photography

The IT-revolution in oncology

This article was first published in Teknisk Ukeblad in Norwegian on 23 June 2020. Scroll down for a version in Norwegian.

EHiN, E-Health in Norway, is Norway’s largest conference on the digitalization of the health sector. Save the date 10-11 November 2020!

“At EHiN you will meet the key players of the health sector, politicians and decision-makers,” said Ketil Widerberg, general manager of Oslo Cancer Cluster.

EHiN has proven to be an important arena to gather the industry, the public sector and the research environment around the digitalization of the health sector.

“During two days, we will learn from one another and share knowledge about technological solutions to benefit the health service and individual patients. This creates a basis for further collaboration,” Widerberg said.

Oslo Cancer Cluster is a non-profit member organization that connects public and private key players in cancer research and a Norwegian Centre of Expertise since 2009. Oslo Cancer Cluster is a collaboration partner in EHiN.

Artificial intelligence changes cancer treatments

Digitalisation is a central area in cancer research and the advent of precision medicine demands that different academic disciplines work closely together. Using artificial intelligence will be important to develop new treatments.

“Artificial intelligence will change how we treat cancer. It is about understanding cancer. The same way that a microscope can show us what cells look like, AI can help us to discover patterns we never would have seen otherwise.

“This makes it possible to give patients personalized treatments because we can identify how the patient will react to the treatment. Eventually, modern machine learning systems will make the treatments even better.

“The goal is to give the right treatment to the right patient at the right time,” Widerberg explained.

The IT-revolution in the oncology field is also of great interest to the tech industry. It is about handling enormous amounts of health data through storage, analysis, machine learning, pattern detection and secure connections between different data sources.

“Personalized medicine, genetics and the use of health data is quickly developing into one of the most important areas in digital health.”
Ketil Widerberg, general manager of Oslo Cancer Cluster.

“EHiN wishes in collaboration with Oslo Cancer Cluster to build Norway as an important international hub in the area of e-health,” Widerberg said.

The programme for EHiN 2020 is currently under development. Information about the venue and ticket sales will be announced at a later date. Please visit the official EHiN website for updates on how corona affects EHiN 2020.

 


IT-REVOLUSJON PÅ ONKOLOGIFELTET

EHiN, EHelse i Norge, er Norges største konferanse om digitalisering i helsesektoren. – Merk deg datoene 10. og 11. november allerede nå.

På EHiN møter du de fremste aktørene i helsesektoren, politikere og beslutningstakere, sier Ketil Widerberg, daglig leder i Oslo Cancer Cluster.
EHiN har vist seg å være en viktig arena for å samle næringsliv, offentlig sektor og forskning rundt digitalisering av helsesektoren.

– I to dager i  skal vi lære av hverandre og dele kunnskap om teknologiløsninger til det beste for helsevesen og enkeltpasienter. Det skaper grobunn for videre samarbeid, poengterer Widerberg.

Han forteller at Oslo Cancer Cluster (OCC) er en non-profit medlemsorganisasjon som samler offentlige og private aktører innen kreftforskning, og et Norwegian Centre of Expertise. OCC er samarbeidspartner i EHiN.

Presisjonsmedisin

Presisjonsmedisin krever ifølge Widerberg at forskjellige fag-grener jobber tett sammen, og digitalisering er et sentralt område innenfor kreft. Han trekker frem betydningen av kunstig intelligens (AI).

– AI vil endre kreftbehandlingen. Det handler om å forstå kreften. På samme måte som mikroskopet tar oss helt ned på cellenivå, vil AI hjelpe oss til å se et mønster vi aldri ellers ville oppdaget. Dette gjør det mulig å gi pasienter individbasert behandling – nettopp fordi vi kan se et mønster på hvordan pasienten reagerer på behandlingen. Etter hvert vil moderne selvlærende datasystemer gjøre behandlingsmetodene bedre.
Målet er å gi den rette behandlingen til den rette pasienten til rett tid, forklarer Widerberg.

IT-revolusjonen på onkologifeltet har også stor interesse for IT-bransjen. Det handler blant annet om å håndtere enorme mengder helsedata gjennom lagring, analyse, maskinlæring, mønstergjenkjenning og sikker kobling av forskjellige datakilder.

– Persontilpasset medisin, genetikk og bruk av helsedata utvikler seg snart til et av de viktigste områdene innen digital helse, sier Ketil Widerberg, daglig leder i Oslo Cancer Cluster.

– EHiN ønsker i samarbeid med OCC å bygge Norge som en viktig internasjonal hub på området e-helse, avslutter Widerberg.

Følg med på ehin.no hvordan koronaviruset påvirker EHiN 2020.

Christine Wergeland Sørbye, CEO of Oslo Science City, is happy to welcome Oslo Cancer Cluster as a member of the new innovation district. Photo: Oslo Science City

Oslo Cancer Cluster becomes a member of Oslo Science City

How can we solve societal challenges, such as cancer, by creating a power centre for innovation in Oslo? This is the key question Oslo Science City – the first innovation district in Norway – hopes to answer.

The ambition of Oslo Science City is to become a world leading innovation district that contributes to research excellence, jobs creation, the green shift and sustainable economic development.

“We intend to develop a vibrant city area where people meet to innovate and explore what we still don’t understand,” said Christine Wergeland Sørbye, CEO of Oslo Science City.

In order to achieve this, Oslo Science City’s strategy is to facilitate cooperation between leading research groups, students, businesses and the public sector. Key actors in the district, including the City of Oslo, Oslo University Hospital and the University of Oslo, are now working together to facilitate the development of the area.

“We will develop a powerhouse for innovation, research and business, and a good place to live,” said Wergeland Sørbye.

Oslo Cancer Cluster joined Oslo Science City in June 2020 to contribute to boosting innovation in this knowledge-intensive area.

”Innovation thrives where there are hard problems that need to be solved,” said Ketil Widerberg, general manager of Oslo Cancer Cluster.

“Cancer is one of the major societal challenges we face today. For over a decade, Oslo Cancer Cluster has worked tirelessly to enable researchers and investors, private companies and public hospitals to work closer together to solve this challenge. We have succeeded in some first steps, now is the time to get to the next level. Utilizing the potential in immunology and digitalisation with Oslo Science City will be key to achieve this.”

Ketil Widerberg, daglig leder, OCC

Ketil Widerberg, general manager of Oslo Cancer Cluster, sees the potential of connecting immunology and digitalisation in the future innovation district. Photo: Oslo Cancer Cluster / Stig Jarnes

Wergeland Sørbye is happy to welcome Oslo Cancer Cluster as an active partner in developing Oslo Science City:

“Oslo Cancer Cluster has unique competencies and a long track record, and we are looking forward to learn from you! Together with the University of Oslo, SINTEF, Oslo University Hospital, the City of Oslo and our other members, Oslo Cancer Cluster will play an important role in realizing the potential for innovation, new jobs and value creation. It is important, and it will be fun!”

Oslo Cancer Cluster Innovation Park, the Oslo University Hospital research building and Norwegian Radium Hospital are located in the new innovation district Oslo Science City.

Oslo Cancer Cluster Innovation Park, the Oslo University Hospital research building and Norwegian Radium Hospital are located in the new innovation district Oslo Science City. Photo: Oslo Cancer Cluster / Christian Tandberg

A vibrant area to live, work, play

There are many innovation districts around the world, yet there is no fixed recipe for how successful innovation districts are developed.

“Developing such an area could be described more as an art than science.” Wergeland Sørbye said.

“However, research highlights the need for certain key functions. For example, you need strong anchor institutions that attract other actors, such as a university or university hospital, and you need to facilitate the cooperation based on trust between the different organizations and stakeholders in the area. Many do this by establishing a joint membership organization, which is what we did with Oslo Science City.”

Furthermore, it is essential to develop a multifunctional area with a critical mass of knowledge-intensive businesses. The ideal innovation district is a vibrant place where people can “live, work and play”, with services and cultural functions. It must also be easy to move around in the area, on foot, bike or public transportation.

“A key lesson from other innovation districts is the importance of adapting to the local context,” Wergeland Sørbye said.

However, no one has previously developed innovation districts in Norway. This makes it valuable to learn from international examples. Some innovation districts that have provided inspiration in the endeavour to develop Oslo Science City are Stockholm Science City, Copenhagen Science City, White City in London and Kendal Square in Boston.

Please follow the Oslo Science City official website for further updates on the development of the innovation district.

New member: Hemispherian

Image of Oslo Cancer Cluster Innovation Park

In this article series, we will introduce the new members of our oncology cluster.

Our newest member Hemispherian is developing a better treatment option for patients with aggressive brain cancer.

Glioblastoma multiforme is one of the most aggressive types of cancer that begins within the brain. Current treatment options are limited to surgery, radiotherapy and chemotherapy, the median overall survival after diagnosis is only 15 months and is highly dependent on the success of the surgery.

A Norwegian company called Hemispherian is advancing a new method to treat glioblastoma multiforme. The molecules the company is developing are called GLIX1 and GLIX5. They target a mechanism that is unique to cancer cells and does not affect normal healthy cells. The molecules are highly toxic to cancer cells and have minimal side effects.

We talked to Adam Robertson, Chief Scientific Officer in Hemispherian, to find out more about the company and the research.

How is Hemispherian involved in health and cancer?

“We are advancing first-in-class therapeutics for the indication with the greatest unmet need in oncology — glioblastoma multiforme. Patients diagnosed with glioblastoma multiforme have dismal outcomes. Overall survival is measured in months with quality of life deteriorating rapidly. It is Hemispherian’s mission to provide superior treatment options.” Adam Robertson, Chief Scientific Officer, Hemispherian.

Why did Hemispherian become a member of Oslo Cancer Cluster?

“As a company focusing on developing cancer treatments Oslo Cancer Cluster is a natural fit for us. We are interested in Oslo Cancer Cluster’s extensive experience in the field and hope to benefit from advice and to make valuable contacts through Oslo Cancer Cluster’s network.” Adam Robertson, Chief Scientific Officer, Hemispherian.