Armend Håti, CEO of ClexBio, received the Healthcare Prize from Trine Loe, Executive Vice President, DNB ASA, at DNB Nordic Healthcare Conference 2022.

Health companies gained investors’ attention

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Strong Norwegian oncology presence at DNB Nordic Healthcare Conference 2022.

The DNB Nordic Healthcare Conference was back with in-person attendance last week, connecting some of the best Nordic health companies with eager investors at the DNB main office in Oslo.

“Health is key in Norway’s transition to a green economy. DNB shows great social responsibility by bringing together key players in business, investment, and health. It is encouraging to see the high-quality of the companies at this conference,” commented Ketil Widerberg, general manager at Oslo Cancer Cluster.

The conference included four different sessions with company presentations. A total of 14 members from Oslo Cancer Cluster were there, demonstrating the first-class cancer innovation emerging from Norwegian research environments.

The podcast Radium, produced by the investment fund Radforsk, also recorded an episode with perspectives on where the Nordic healthcare sectors.

 

Up-and-coming companies competed

Eleven health start-ups competed for the Health Prize of NOK 1 million during the Venture Session. Six members of Oslo Cancer Cluster were selected for this competition, and two were fast-tracked for the final. Here are snapshots from their pitches:

Bjørn Klem presented Adjutec Pharma, a company fighting against the global crisis of anti-microbial resistance.

Kerstin Jakobsson presented Kongsberg Beam Technology, a medtech start-up developing the next generation’s proton radiation therapy, by personalising the treatment for each patient.

Katja Vetvik presented Thelper, a Norwegian company that is developing targeted immunotherapies against cancer.

Peter W. Eide presented Oncosyne, a company that will provide game-changing functional diagnostic tools that give cancer patients significantly better and longer lives.

Torbjørn Furuseth presented DoMore Diagnostics, a company that is transforming cancer diagnostics with artificial intelligence.

Adam Robertson presented Hemispherian, a company developing a pipeline of first-in-class epigenetic therapeutics against aggressive cancers.

The companies ArxxTherapeutics, Bulbitech, Clexbio, Helseboka and Nadenod also pitched in this session. After a nerve-racking final, with heated discussions in the investor panel and a packed auditorium voting for their favorite start-up, Clexbio won the prestigious prize.

 

Oncology companies drew a crowd

There were two sessions with listed companies and one session with private companies, including 9 members from Oslo Cancer Cluster in total. The rooms filled up quickly, and the companies received many questions from curious investors. Here are some messages from their presentations.

Dan Schneider, CEO of Photocure, described how the company is improving the lives of bladder cancer patients with unique photodynamic technology for diagnosis and treatment. Visit the Photocure website to learn more.

Jan Alfheim, CEO of Oncoinvent, presented how the company uses alpha-emitting radiotherapeutics to kill all cancer cells in body cavities, including micro-metastatic disease. Visit the Oncoinvent website to learn more.

Martin Olin, CEO of BerGenBio, introduced how the company uses targeting AXL inhibitors to prevent the progression of cancer.

Visit the BerGenBio website to learn more.

 

Namir Hassan, CEO of Zelluna Immunotherapy, talked about how the company wants to save lives through innovative cancer-targeted cell therapies, using the unique TCR-NK technology.

Visit the Zelluna Immunotherapy website to learn more.

 

Per Walday, CEO of Exact Therapeutics, informed about how the company improves drug delivery with an ultrasound technology platform, using specifically designed microbubbles.

Visit the Exact Therapeutics website to learn more.

 

Mikael Engsig, CEO of Nykode Therapeutics, addressed how the company’s unique vaccine technology platform has the potential to be applicable to several disease areas.

Visit the Nykode Therapeutics website to learn more.

 

Carlos de Sousa, CEO of Ultimovacs, focused on the company’s next-generation universal cancer vaccine, that can educate the immune system to recognize telomerase, an enzyme that is expressed in 85% of all cancer types.

Visit the Ultimovacs website to learn more.

 

Erik Wiklund, CEO of Targovax, spoke about how the company wants to make PD1 checkpoint inhibitors work for all patients, with the company’s oncolytic therapy.

Visit the Targovax website to learn more.

 

The conference was organised by DNB with support from Oslo Cancer Cluster and Norway Health Tech. The event also collaborates with the following Norwegian clusters and networks in healthcare: The Life Science Cluster, Norwegian Smart Care Cluster, The Life Science Cluster, Norwegian Inflammation Network, Nansen Neuroscience Network and Aleap.

The post Health companies gained investors’ attention first appeared on Oslo Cancer Cluster.

Photo: Kenta Kikuchi, Unsplash

10 highlights from Oslo Cancer Cluster 2022

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Scroll down to see our 10 highlights of the year.

2022 has been a year of post-pandemic growth for us, where we have revitalised the team, made new collaborations across borders and raised our voice on political issues. We have also started new initiatives, created more meeting places and welcomed new members to our community. Find out how you can engage with us in the snippets below.

 

Growing our community

We are nothing without our members. This year, we welcomed 10 new members to our cluster, strengthening our position as one of Norway’s leading health clusters.

The membership base spans different sectors of society, including: academia, drug development, technology, human resources and recruitment, legal firms, clinical service providers, investment funds, and more. The size of our members ranges from one-person companies to multi-national corporations. The one thing all members have in common is the motivation to work together to accelerate the development of cancer treatments and diagnostics.

Make some new connections! Please visit our Member Overview to see who else is part of our cluster.

New members of Oslo Cancer Cluster in 2022.

 

Arranging popular meeting places

Meeting places are the heart and soul of our organisation. This is where people meet to discuss how to accelerate the development of cancer treatments and diagnostics. Whether your interest lies in educational forums, political debate, partnering opportunities, networking with colleagues or meetings with investors, we have a tailored event for you. Here are a few from the year gone-by:

  • Cancer Crosslinks, an annual event with talks from some of the most renowned cancer researchers in the world, accompanied by lively interactions between the participants, took place in January.
  • Fremtidens kreftbehandling was arranged in April and August, offering vibrant political discussions between patients, politicians, clinicians, and industry representatives.
  • The Summer and December Gatherings, two networking events for our members and stakeholders to get to know one another in an informal setting, were organised in June and December.
  • NLSDays brought us to Malmö (Sweden) in the end of September. We promoted Norwegian life science in a joint booth and helped our members achieve the most from their partnering.
  • DNB Nordic Healthcare Conference, a unique place for investors to meet with start-ups in the Norwegian healthcare sector, takes place in December.

Did these teasers spark your interest? Please visit our Event Calendar to register for events.

Our events offer educational forums, networking opportunities and new arenas for cooperation. This photo was taken at a satellite meeting in connection with Onkologisk forum 2022. Photo: Fartein Rudjord / CONNECT

 

Building successful companies

Similar to how an incubator provides a warm, nurturing growth environment for babies, Oslo Cancer Cluster Incubator helps early-stage cancer start-ups develop into successful businesses.

This year, five companies from our Incubator (DoMore Diagnostics, Thelper, Adjutec Pharma, Kongsberg Beam Technology and OncoSyne) were selected for the DNB Nordic Healthcare Conference’s Venture Session. Several companies pitched at NLSInvest, at BioStock Life Science Summit and were also featured in the International Cancer Cluster Showcase digital brochure.

As a recognition of the Incubator’s accomplishments, SIVA extended their financing for another year with NOK 3,5 million. This means we can continue to help cancer start-ups grow and develop life-saving treatments.

Interested in the services and facilities at Oslo Cancer Cluster Incubator? Visit their website or contact Janne Nestvold, COO of Oslo Cancer Cluster Incubator, to schedule a visit.

Janne Nestvold, COO of Oslo Cancer Cluster Incubator, takes an active and hands-on approach when developing the cancer start-ups. This photo was taken at the Biostock Life Science Summit 2022. Photo: Elisabeth Kirkeng Andersen

 

Connecting public with private

There is a wave of promising cancer treatments coming in the field of precision medicine. Still, questions remain about how to quickly get these implemented in the Norwegian healthcare system.

The public-private consortium CONNECT was set up in 2021 by 22 founding partners to drive the implementation of precision cancer medicine in Norway, with Oslo Cancer Cluster as project manager.

During 2022, CONNECT has held a long line of educational seminars, grown to include 30 partners, created a positive climate for public-private collaborations in cancer, and put Norway on the map for precision cancer medicine internationally, most notably in a Letter to the Editor in Nature Medicine.

Get engaged in CONNECT! Please visit the CONNECT website or contact Jutta Heix, Project Lead in CONNECT and Head of International Affairs in Oslo Cancer Cluster.

In CONNECT, stakeholders from both the public and private sector work together to drive the implementation of precision cancer medicine. This photo was taken at one of the Steering Committee meetings in 2022. Foto: Fartein Rudjord

 

Making our voice heard

We fight for political change, so cancer innovation in Norway can thrive. One way of doing this is by affecting the framework conditions, such as national policies, governmental strategies and state budgets.

That is why we had an active presence at Arendalsuka 2022, where we held meetings together with our partners, talked to politicians and promoted topics that are important for our members.

We also had a record number of on-site visits by curious politicians that want to learn more about our cancer eco-system.

Help us affect political change! Read all our input or get in touch with Wenche Gerhardsen, Head of Communications at Oslo Cancer Cluster.

Three people outside a building.

Jan Christian Vestre, Minister of Industry, received a tour of Oslo Cancer Cluster Innovation Park, by Ingrid Stenstadvold Ross, general secretary of the Norwegian Cancer Society, and Ketil Widerberg, general manager in Oslo Cancer Cluster, in August 2022. Photo: Oslo Cancer Cluster

 

Inspiring homegrown talent

We want to raise the next generation of cancer researchers. That is why we have a collaboration with Ullern Upper Secondary School, where we take students out of the traditional classroom setting and give them a taste of what life as a researcher or health professional is like.

During 2022, we arranged work placements for the students and a thematic day together with clinicians from the Radium Hospital. We also had good news from several Ullern alumni, including Simone Mester becoming CEO of start-up Authera and Ullern students winning EU Science Competition.

We know these students can become the entrepreneurs, inventors, researchers and talents that the Norwegian life science environment needs. We are proud to help inspire them.

How can you help inspire the young? Read more on the website or get in touch with Bente Prestegård, Project Manager in Oslo Cancer Cluster.

 

Joining the European efforts

The European Union has launched a Cancer Mission with the goal to improve the lives of 3 million people living with cancer by 2030. We want to position Norway to help this ambitious endeavour.

In 2022, we launched a national Cancer Mission Hub together with key players in the Norwegian cancer field. The hub will inform about EU opportunities, mobilise the Norwegian stakeholders and foster collaboration between all participants.

Get engaged with the hub! Read more on the Cancer Mission Hub website or get in touch with Marine Jeanmougin, EU Advisor in Oslo Cancer Cluster.

 

Strengthening the team

We employed two new team members to meet the demands of all ongoing activities.

Marine Jeanmougin, our new EU advisor, brings aboard scientific expertise and has unique perspectives into European affairs. You can contact Marine for help with applications to EU funding and for information on upcoming EU calls.

Marine Jeanmougin, EU Advisor, Oslo Cancer Cluster

Dave Tippett, our new Membership advisor, is an administration wizard that helps the team, our members and everyone in the office become more efficient. Dave splits his time between Oslo Cancer Cluster and the Incubator to ensure that things are running smoothly, so the researchers have time to focus on what they do best.

Dave Tippett, Membership advisor, Oslo Cancer Cluster

For general queries, please visit our Team page to find out who to contact.

 

 

Click here to read selected milestones from our biotech members in 2022

The post 10 highlights from Oslo Cancer Cluster 2022 first appeared on Oslo Cancer Cluster.

Photo: Moritz Knoringer, Unsplash

10 milestones from our biotech members in 2022

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What a year it has been for the development of Norwegian biotech companies!

We want to recognise the accomplishments of our members this year. Many of them have reached impressive milestones and unfortunately we can’t include all. So we have selected 10 outstanding news stories. These represent both big and small companies, covering various sectors and focusing on different types of cancer therapies and diagnostics. We hope this list serves as inspiration for you and that you get to know our members a bit better.

Strategic collaboration on optimizing TCRs

Nextera set up a strategic collaboration with Zelluna Immunotherapy in March. Together they will optimize T cell receptors (TCRs), which are crucial in the development of a special type of cancer treatment called TCR-based natural killer cell therapies. Nextera is a research-based target and drug discovery company with a unique protein engineering and discovery platform – NextCore.

Read the press release

Faster development of cancer vaccines

NEC Oncoimmunity acquired VAXIMM’s neoantigen vaccine development assets in March. These assets will be used to faster develop personalized T cell cancer vaccines. NEC OncoImmunity AS is a biotechnology company that has developed a machine-learning software to enable development of personalized cancer immunotherapy, in addition to infectious disease vaccines.

Read the press release

Photo of Richard Stratford and Trevor Clancy in OncoImmunity.

Richard Stratford and Trevor Clancy, founders of NEC OncoImmunity AS, an AI driven biotechnology company. They grew the company in the Oslo Cancer Cluster ecosystem, making use of the cluster’s advice and support, and networking and partnering opportunities. The photo was taken in December 2018 outside Oslo Cancer Cluster Innovation Park. Photo: Oslo Cancer Cluster

 

Artificial intelligence improves cancer prognosis

In May, DoMore Diagnostics became the first company ever to get a CE-mark for a product that utilises artificial intelligence to improve patient outcomes. The company has developed a deep learning algorithm that can give more accurate prognosis for colorectal cancer patients by analysing standard histology images.

Read the press release

The deep learning algorithm that DoMore Diagnostics is commercialising was first invented by Professor Håvard Danielsen at the Institute of Cancer Genetics and Informatics, also situated in Oslo Cancer Cluster Innovation Park. Danielsen received the King Olav V’s Cancer Research Award in 2022 for his research into artificial intelligence and cancer. Photo: ICGI

 

Alpha emitter therapy against colorectal cancer

Oncoinvent initiated a phase 2 trial for colorectal patients to be treated with their drug candidate Radspherin in August. The study will be conducted at two sites (the Radium Hospital in Norway and at Uppsala University Hospital in Sweden) and the first patient was included in August. Oncoinvent is a clinical stage company advancing alpha emitter therapy across a variety of cancers.

Read the press release

Takeda Ventures invests in TCR-NK therapies

Zelluna Immunotherapy received an investment from Takeda Ventures Inc. during the company’s financing round in August. The funds will help advance the company’s lead product. Zelluna Immunotherapy is a company pioneering the development of a new type of treatment against solid cancers called “allogeneic T cell receptor guided natural killer cell immunotherapies”.

Read the press release

Zelluna Immunotherapy have enterred several strategic collaborations this year, including with Takeda Ventures and Nextera. This photo was taken of the Zelluna Immunotherapy team at Oslo Cancer Cluster Innovation Park. Photo: Zelluna Immunotherapy

Digital platform for research collaboration

Ledidi revealed the company’s software technology will be used in UK hospitals to improve the treatment, prognosis and care of patients with breast cancer in September. It is the pharmaceutical company Pfizer’s UK branch that is offering subscription access to NHS hospitals for the cloud-based research and registry platform Ledidi Core. Ledidi is a Norwegian technology company with an end-to-end solution for health registers and research.

Read the press release

Einar Martin Aandahl, founder and CEO of Ledidi, developed the research platform because as a clinician he saw a need for simpler collaboration on data between doctors, institutions and countries. Photo: Ledidi

 

Promising results for universal cancer vaccine

Ultimovacs announced positive three-year results with 71% survival rate for patients in the first cohort of a study into metastatic malignant melanoma in October. The patients had been treated with the company’s product UV1 (a universal cancer vaccine) in combination with pembrolizumab (a checkpoint inhibitor anticancer drug). Ultimovacs is an immunotherapy company developing immune-stimulatory vaccines to treat a broad range of cancers.

Read the press release

Oncolytic peptide against melanoma

Lytix Biopharma expanded the ATLAS study to three European countries in November. ATLAS is a phase 2 combination study, treating patients with advanced melanoma with the company’s product LTX-315 (a first-in-class oncolytic molecule) and pembrolizumab (a checkpoint inhibitor anticancer drug). Lytix Biopharma is a clinical stage biotech company developing novel cancer immunotherapies.

Read the press release

Light cytoscopy against bladder cancer

Photocure’s partner Asieris enrolled the first patient in a phase 3 trial exploring the use of Hexvix and blue versus white light cystoscopy in patients with non-muscle invasive bladder cancer in November. Hexvix is a drug that preferentially accumulates in cancer cells in the bladder, making them glow bright pink during blue light cystoscopy. This makes it easier to detect and diagnose tumours.

Read the press release

Immunotherapy against cervical cancer

Nykode Therapeutics continues to show positive results from the company’s phase 2 clinical study against cervical cancer in November. The patients in the study have received Nykode Therapeutic’s VB.10.16 (a therapeutic vaccine for the treatment of human papilloma virus-16 induced malignancies) and atezolizumab (a checkpoint inhibitor anti-cancer drug from Roche). Nykode Therapeutics is a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel immunotherapies.

Read the press release

 

Would you like to have your company’s news story featured on our website? Please get in touch with Sofia Linden, Communications adviser at Oslo Cancer Cluster.

The post 10 milestones from our biotech members in 2022 first appeared on Oslo Cancer Cluster.

The Incubator helps cancer companies grow, led by Janne Nestvold, COO, and Ketil Widerberg, CEO & Chairman. Photo: Wenche Gerhardsen / Oslo Cancer Cluster

Cancer incubator secures further financing

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SIVA continues backing our Incubator so we can help cancer start-ups succeed

Oslo Cancer Cluster Incubator has been awarded NOK 3,5 million to continue supporting cancer innovators during 2023. The funds come from SIVA, a governmental enterprise facilitating a national infrastructure for innovation.

Why are these funds important? Well, the road is long from a promising innovation is born until it becomes a solution that improves patients’ lives. An innovator often needs support to make their idea into a commercial product.

Precision therapy against cancer

This was the case with Kongsberg Beam Technology, founded by Per Håvard Kleven who had invented a digital solution to improve proton therapy, based on expertise from the Kongsberg defence industry.

The company was admitted into the Accelerator programme at Oslo Cancer Cluster Incubator in 2019. The incubator team worked closely with the company and helped with everything from setting up a business plan, developing a company strategy and recruiting management, to attracting the company’s first investors.

Kerstin Johansson, CEO of Kongsberg Beam Technology, one of the companies in the Incubator that has received help from SIVA.

“If it wasn’t for Oslo Cancer Cluster Incubator, Kongsberg Beam Technology wouldn’t be where we are today.”

“If it wasn’t for Oslo Cancer Cluster Incubator, Kongsberg Beam Technology wouldn’t be where we are today. From being a one-man company, we have grown to a semi-virtual company with a mix of employees and CRO/service companies with key competences for the road to commercialise our product MaMa-K. To date we have attracted NOK 50,4 million in private investments and public funding. We strongly believe that with our solution, MaMa-K software intended for radiation therapy the clinical benefits will be significantly better and cancer patients will have a much better life with less side effects after the treatment,” said Kerstin Jakobsson, CEO of Kongsberg Beam Technology.

A melting pot for innovation

Oslo Cancer Cluster Incubator is the only cancer incubator among the total 35 companies accepted into the SIVA’s new ten-year Incubator programme starting 2023. The Incubator offers business development services, state-of-the-art laboratories, and access to a global cancer community.

Oslo Cancer Cluster Incubator have state-of-the-art labs that are shared between academics and private companies. Photo: Christopher Olssøn

A multitude of languages can be heard between the international researchers as you walk down the hallways. When peering into the labs, you see academics working side-by-side with private companies. This is a true melting pot for health innovation.

“Oslo Cancer Cluster Incubator is uniquely situated next to Oslo University Hospital and can provide the network in oncology that early-stage companies in cancer need.”

“Oslo Cancer Cluster Incubator is uniquely situated next to Oslo University Hospital and can provide the network in oncology that early-stage companies in cancer need. We are now expanding the Innovation Park to make room for more companies, who are in dire need of our facilities and expertise. This is good for the companies, it benefits the patients and adds value to Norwegian society,” said Ketil Widerberg, CEO and Chairman of Oslo Cancer Cluster Incubator.

The Incubator is situated in Oslo Cancer Cluster Innovation Park, right next to the Cancer Research Institute and a stone’s throw away from the Oslo University Hospital (a Comprehensive Cancer Centre). Photo: Christian Tandberg

The post Cancer incubator secures further financing first appeared on Oslo Cancer Cluster.